Monday, September 30, 2019

Life Define Leadership Essay

What is the leadership? I often ask myself. Leadership is a very abstract concepts, some people don’t have a way to go to real life define leadership, even if he is now running a large company even leadership a country. Because of its category is too big. Through a few weeks of classroom study, I gradually with the own leadership definition, began to try to explore what is leadership. Before work experience, also have to lead a team, but have no real system to learn what the leadership is. Below the article I will explain the leadership in my heart. Leadership is a process of getting things done through people, in the textbook, we begin to contact the Leadership of the theory of knowledge, also in class, through a few small games, such as Marshmallow tower, practice Leadership. The textbook says the three types of leadership, democratic, authoritarian, laissez faire, I think, real leadership is difficult to directly will these separate, and they will fusion these types. In different times and different situation, displays the different style, this is the true leaders. If simple to put a person’s leadership types are classified it is very one-sided. We can only say they are more inclined to what kind. For example, I will talk about my personal experience. When I was a universities’ student in China, I opened an e-commerce company, it called Universities’ cell phone union of China and seven people went into business together for the company, they were students too, I was in them as leader. At first, everyone has great enthusiasm, is with a passion of the cavity work, also rely on my personal charm, because we were both have no money, no experience. Many companies have to work things, such as do website, hair handbill, wait a tired of live. But the work is not ideal, the company does not have profit, after period of time, they began to lose patience, lose passion. They all wanted to give up. Someone suggested, just gave it up, and then strive on useless. And this time, as a team leader, you must stand up, with authoritarian way hold on, in the spirit up motivate them, use the positive spirit to inspire them. Let them think we are a team and never give up. To hold on, we will be successful. This is a very often in the startup problem, if the team leader without certain perseverance and decision making, it is difficult to spend the difficulty. Fortunately, we pass the difficulties, the website has begun to have customers, and someone is looking for us to buy cell phones, gradually have profit. But problems also began, the team started seven of the site’s planning the divergence web site is primarily sell mobile phone, but on the web site are beginning to target customers later, they want to sell other things on the site, and cell phone extraneous matter. This time is to do or do all fine. It is hard to the choice. This time, I had a meeting, and let people talk of the company, through the very democratic way to listen to their views, summarizes the advantages and disadvantages of each, weigh the advantages and disadvantages and website decided to continue to sell mobile phone, the industry bigger, which is conducive to the next development. Through three years of operation, we market distribution in 20 provinces, under the small team have 300 university student, have the same administrative headquarters, we formed a good few department, the finance department, the Marketing Department, human resources department, technology department, administration department. Form a comparison of the regulation of the company. I can say, the company exercise great leadership skills. Also in the actual experience accumulated a lot of experience for leadership. Leadership means responsibility. It’s adventure and often fun, but it always means responsibility. The leader is the guy the others look to get the job done How to use the leadership knowledge . There are many leadership case analysis, or Project, and emphasizes the grasp of the business world now, after the study of the leadership course, we can easily see clear a enterprise under the surface of the actual operation of the means, the enterprise strategy, culture, capital, etc. Of course these to personal future career will not have a direct function, but it is an indispensable exercise. The future of my leadership From the leadership class let me from thinking came out, let me know a completely different world, let me made clear the idea of starting my own business. I believe the leadership value, also hope to have more students, no matter whether have the class and have joined the innovative team . let us together to do some different things, and not waste their own intelligence and one cavity warm blood. You are not a finished leader. No one ever is, not even a president or prime minister. But you are an explorer of the human mind because now you are going to try to learn how to get things done through people. This is one of the keys to leadership. So I will change my style and try different kinds of leadership style in the classroom. Constantly to experience feel, this is advantageous to the development of future better. I have enjoyed this class that can let me know some different things. The teacher has many ways to help the student know some leadership knowledge like the small games. And you are very easy to master this theory, also easy to define. You can use knowledge be applied to real life. Thank you for the teacher.

Sunday, September 29, 2019

Color of Water Essay Essay

What factors contribute to who you are today? A question that many struggle with including James McBride, the author of The Color of Water. James struggled with finding himself because of his mixed background, a white Jewish mother and a Black father. When James finally gets an understanding of the culture, races, and religions that surrounds him it helps him to gain his own identity, point of view, and allows him to share his experiences with others who may be going through the same things in his writing. As James enters many different cultures he comes to realize what type of surrounding and life he wants for himself when he visits his sister jack in Louisville, Kentucky. The culture in Louisville was very violent. James and his friends participated in illegal activities such as breaking into cars, shoplifting, and doing illegal drugs (McBride 139). After complaining about life, doing illegal things, talking to Chicken Man a man that sat on the corner on a crate, and drank alcohol all day who told James that no one will know who are you unless you make something of yourself and that sitting on the corner all his life is a bad decision (150), and taking Jack’s advice, â€Å"you have to choose between what the world expects of you and what you want for yourself† (161), he enrolls back into high school and later goes on to Oberlin College. Growing up James’ mother Ruth always tells him that white people are no good, but as a young adult his perspective changes altogether. As James completes high school and early into college a white lady by the name of Mrs. Dawson who donated most of her time and money to inner city kids sponsors James to be able to go to Europe and travel with the American Youth Jazz Band and continues to help him get into graduate school. When James’ friends in college talk about how all white people are rich and they have no problems James had no choice, but to agree because of the surrounding he was in, but in his mind he was strongly disagreed with the statement that had just been made having just read the letter from Mrs. Dawson about her husband dying suddenly of cancer (187). Church plays a big part in James’ life. As a kid James goes to church every Sunday and experiences people crying and being uplifted. Also his father starts the New Brown Memorial Church, which James goes back to visit later in life. From going to church every Sunday James develops his own relationship with God after he goes through the part of his like where he is very rebellious and disobeys the law. After he enrolls back into school he turns to God to ask him for strength (161). This shows James getting his own opinion from God and his religion instead of just going to church because he’s being going all his life. Suffolk had begun to suffocate me. The isolation my family felt, the heartbreak they had suffered† (223). James researching into his mother’s history shows him why he went to Jewish schools instead of the public schools, what happens in Suffolk that causes Ruth to leave, start a new life, and become very secretive. Heritage is important because it lets you know what struggles, accomplishments, etc. your family has overcome, why things are the way they are, and how you can continue a tradition, or better understand who you are. Knowing about my Mother and Father’s background gives me an idea of what our family is about and what type of things I should stand for, or if I believe in the same things that my parents believe in. Learning about heritage and the different factors that make up his surrounding James McBride finds his identity, gains his own opinion, and point of view. Reading The Color of Water and going through this experience along with James encourages others to learn more about their heritage and who they are, and if you already have that information interpret it into a way that benefits you and can maybe even help someone else.

Saturday, September 28, 2019

Cars Produced at Eros Motors

At Eros Motors, we provide safe, stylish, green and a cutting edge form of individual mobility to our customers. We have been successful in offering what customers feel is important to them. Our cars also come with all the options, which are asked by our customers. We planned our strategy taking into consideration all the aspects of marketing, H. R, finance and operations. Marketing plays a very crucial role in this modern world so we promoted our products through various forms of media. We spent heavily at the start just because we wanted to make our presence felt in the market.We always believed that our team is of utmost importance to us, so we made sure that there is a balance between automation and workforce to maximize production. We also paid them well so that they remain motivated at all times and work towards the goal of the company. Training of employees is a must and this is necessary for the quality of the cars. We noticed that our Warranty claims were high, so by proper training this could have only been reduced. Research and Development is an important area and a good amount of money was spent over the years so that we develop better and environment friendly cars in the times to come.We made sure that the money is not spent on general R&D rather we identified some key areas and invested in those constantly. Finance was an area of concern as we were incurring huge losses; we took necessary steps to improve this. We priced our products aggressively and planned production efficiently. As a result this gave us better sales. We also tried to cut down on costs, which gave us a better gross margin over the years. We started to make profits in the later years and this shows that our products have been well accepted by the market.We offered Alpha (medium) and Beta (large) cars in the beginning then we came up with Delta (city – hybrid) and lastly with Zeta (diesel – luxury). The luxury market was untapped and we thought we could do well by se lling a small number of cars because the margins in a luxury car are huge. The offering was based on the market research and the demand in the market. The design of the cars kept on changing as requested by the customers. This showed that we were catering to all segments of the market in terms of offering and pricing.Our aim is to be a leading car manufacturer by creating stylish, reliable, eco friendly cars by following the principles of enhancing our team, extending our business and enlarging our market. To sustain in this competitive market we have to take into account what the competitor is doing and react accordingly by delivering a better product. The need of the hour is to connect with the customers. The world is moving towards alternative fuels and we will also try to come up with products that are environmental friendly keeping in mind the needs of the customer yet giving stylish, value for money and fuel efficient cars.

Friday, September 27, 2019

Information System in Public Sector Organizations Essay

Information System in Public Sector Organizations - Essay Example It is evidently clear from the discussion that with the emergence of modern information technology, firms and government agencies no longer need to take place in the hierarchy. Contrary to the bureaucracies in the past that adopted command and control as well as the inadequate distribution of information, innovation in information technology has made firms and governments to effectively organize what can be done during their day to day operations. Within the public sector organizations, information technology was primarily adopted to automate existing operations and to increase the speed of communication. E-government has therefore positively impacted on the performance of the organizations. This meant that the paperwork and people were replaced by electrons. Before the introduction of internet and extensive use of personal computers, the major objective of technology use in government was enhancing the management effectiveness of the administrators while at the same time increasing the government productivity. With the diffusion of personal computers in the 1980s, public administrators were provided with personal information technology system, leading to a new period of IT use in government systems. On the other hand, learning as a process has positively impacted on the knowledge management. Through learning within the public organizations, knowledge has gained sufficient momentum. Despite the positive implications of e-government and learning, public sector organizations are faced with quite a number of challenges. This paper seeks to discuss the challenges of the implementation of information system in public sector organizations, using the concepts of e-government and learning in theory and in practice. Information and communication technologies (ICTs) were noted to have a strong impact on the way the public administrators performed their duties. For instance, ICT assisted in service and information delivery, the creation of a networked structure for interc onnectivity, effectiveness and efficiency interactivity, decentralization, and accountability among other aspects. E-government entails utilization of internet and the World-Wide-Web to deliver government information and services to citizens.

Thursday, September 26, 2019

Challenges That New Media Poses To the Cinema Industry Essay

Challenges That New Media Poses To the Cinema Industry - Essay Example Modern movie theatres today are perceived as big enclosed buildings with excellent sound effects, comfortable seats, dimmed lights and a big wide screen where the latest international and local movies or films are shown. Movie theatres compared to the televisions are owned by corporations and visited by the general public while televisions are owned by individuals. The film is actually projected with a movie projector onto a large white screen infront of the auditorium. It is connoted as a "big screen" which contrasts the small screens of television to put a thrill and play with a person's imagination when it comes to movie watching. According to a 24 year old movie watcher, movie theatres add more thrill with the use of a larger than life images and loud sound effects. Movie theatres are very popular. Long before television was made known in the 1950's, the first movie theatre which is exclusively showing motion pictures was launch in 1896. Non-commercial television is a system of broadcasting that is financed by means other than advertising revenues. (Paul Mareth) Today however, through the evolution of technology, hi-tech gadgets were being invented. Television is not only used to watch TV shows aired by television programmers and cable/satellites. With the existence of video tapes or video home system (VHS), CD's (compact disk), VCD's (Video Compact disk) and DVD's (Digital Video disk), and the innovation of wide flat screened television sets, it now provides a homely theatre for home entertainment. AIMS To discuss the contribution of the distribution of DVD in peoples lifestyle as a result of home entertainment To know the positive and negative effects of DVD distribution to the cinema industry Film Distribution Since the late 1970's, there has been a radical change in both film content and the distribution of the film product. (Gerald Mast) While more and more people subscribe cable or satellite connections, film industries has come to depend more and more on television rather than theatres. The President of Paradigm, Peter Broderick says "I don't recommend that filmmakers go it alone and try and reinvent the wheel. But I also don't recommend that they just blindly go into making overall deals assuming that all their problems will be solved by this one company, whatever it may be". (Rebort) A film doesn't have to be seen only in theatres with the existence of televisions and the evolution of film distribution. Acknowledging the threat of the growing number of couch potatoes, film doesn't need to be distributed through cinemas alone but also go with the fast flow of digital innovation. Eventually films had been distributed, designed or converted to cater TV viewing, since the early 80's. VC R equipments and video tapes had been popular and widely distributed and so do CD's and DVD's in today's era. However, DVD's won't be around forever. There is this so called "format war" that keeps on

The internet on thinking Research Paper Example | Topics and Well Written Essays - 750 words

The internet on thinking - Research Paper Example (Greenbalt, 776). In answering these questions, traditional thinking can be described and evaluated. In evaluating it, then the impact of the internet on it can be revealed. Traditional thinking is slow. Slow because it requires careful considerations based on many considerations without the help of any readily available resources. The internet has come in and made it faster. At times, thinking has become instanteneous as a result of readily available resources availed by the internet. Traditional thinking involved thinking based on one consideration or just a few. However, with the internet in place now, it has resulted in what may be deemed as an enhancement. Enhancing the way may sources are integrated into thinking. By integrating many sources of information from the internet into thinking, persons are able to think diversely and make highly supported decisions (Greenbalt, 776). As such, the intergration of many sources of thinking has brought about an era of vast amounts of innovation in almost all areas of our lives. This innovation has been rapid as compared to the past. The difference between the era before the internet and this era of the internet is that, in traditional forms of life before the internet, people were ford of linear time, slow face to face connections, centaralised centres of decision making and one-sided decisions (Ã¥ ¸Æ'Ã¥  ¢Ã¥ §â€ Ã¦â€" ¯Ã¤ ¼ ¯Ã©â€¡Å'å‡ ºÃ§â€°Ë†Ã¥â€¦ ¬Ã¥  ¸, 141).But as of now, people have learnt to change their ways of thinking to conform to a fast and mainly instant world that has large concurrent, multi – tasking and synchronized abilities that have been made probable by innovation emanating from the internet. Innovation resulting from new ways of thinking brought about by the internet is very much evident in day to day lives. For example, new services and products are always been revealed at a highly frequent rate. These new innovations are from unprecedented sources and as such, it has

Wednesday, September 25, 2019

Context paper English 105 Essay Example | Topics and Well Written Essays - 500 words

Context paper English 105 - Essay Example Ryves Hall has proved to be a second home for children of all ages in the Terre Haute locality, regardless of race or money. They serve children from ages three to seventeen and all their programs are age related, appropriately designed to benefit the children. Ryves Hall has been offering service to any children who walk in. All the activities provided by the institutions are free for the children. Their primary mission is to assist children and families in Terra haute, which is one of the most impoverished areas in the locality. They serve children who lack educational facilities, unemployment, hunger and poverty. It is the beacon of hope for many young Americans who are deprived of basic necessities in life. Most of the children who attended Ryves can be put under â€Å"at- risk youth â€Å"as they come from single parent, below poverty line and children who do not have anyone to turn to. â€Å"Students from lower socio-economic status are often denied the same luxuries that other students take for granted. These individuals often live in a single parent homes where the mother is the sole financial provider, disciplinarian and caregiver and may face issues such as hunger, live infestations, lack of hot water and inadequate attention† (Miller). Ryves Hall takes care of these children who lack the normal home upbringing. The children who are under their wings are between three and seventeen. Half of them come from minority population. Their main aim is to give them a second chance in life and to bring them up in the best possible way. Living in a home where basic needs as well as guidance are not available can have a negative impact on the children. Ryes Hall acts as their mentor and guides them to be respectable citizens in the society. Most of the children in Ryes Hall display problems associated with having to grow up too early due to lack of proper guidance at home. Many of them have experienced substance abuse, physical abuse, sexual abuse and low

Tuesday, September 24, 2019

Pearson Education Case Study Example | Topics and Well Written Essays - 2750 words

Pearson Education - Case Study Example When the SWOT related perspectives of the company are posited against the STEEPLE - social, technological, economic, environmental, political, legal and ethical - framework of analysis at a macro-environmental level the picture that emerges of the company is essentially a multifaceted business proposition of the current decade (Kallis, Alier & Norgaard, 2009). Pearson Education's SWOT - strengths, weaknesses, opportunities and threats - environment is characterized by a highly competitive external environment of fewer opportunities and more threats as against a highly volatile internal environment of more strengths and equally more weaknesses, the latter arising from competition related phenomena (Clark & Phillips, 2008). Its cultural diversity, organizational culture, supply chain management, employee motivation strategies, modern Human Resource Management (HRM) practices, management structure and style, have contributed in large measure towards this success though as many critics have pointed out the company needs a well defined directional thrust in the current economic and financial turbulence. Articulate business strategy of the company has been responsible for its present achievements in organizational cum corporate objectives though the very direction of the strategy needs a still greater focus on the long term goals rather than the immediate goals (Finlay, 2000). AnalysisPearson Education, proper, as distinct from the Pearson Group is involved in education related activities. These activities can be divided into three broader segments - publishing academic books, publishing non-academic books and education technology related work. Its current operations involving an expansive global network are focused on the North American and European markets (Piercy, 2002). The very strategic perspectives on which the company has evolved have been responsible for its current business strategy. There is a very strong premise on which the company top management has sought to define its growth trajectory. The learning outcomes of this paper would delineate the related aspects of this strategic approach of the company with added emphasis on corporate goals (Mullins, 2005). Changing business strategy of Pearson Education in particular and Pearson Group in general has been responsible for the present revolutionary shift in focus at the company. The underlying principle of this change in business strategy is the successive creation of M&A related synergies through a series of high profile acquisitions and mergers in the recent past (Clarke & Hermens, 2001). This aspect of Pearson Education's organizational behavior requires greater attention because the company has been able to posit itself against competitors with remarkable success due to the positive outcomes related to M&A. The causative elements of this strategic orientation of the company need to be looked at from two different angles. In the first place, Pearson Education is aware of the growing threat of the fast changing technological environment that favors those rivals with technology-based resources. Secondly its own resource base has been expanding at a much faster rate both in diversity and complexity (Davenport, 1994). The latter element includes even

Monday, September 23, 2019

Research Methods and Statistics (Report) Essay Example | Topics and Well Written Essays - 2000 words

Research Methods and Statistics (Report) - Essay Example That is, communication must be determined based on the different dimensions that surround this concept, which include, among others, the ability of the disabled individual to communicate through speech and nonverbal communication, as well as understand communication from other people, or as the message is being transmitted to him/her. When the dependent variable is clearly determined and defined-that is, effectively operationalized-the authors will be able to state the generalizability of the results of the study in terms of communication, and specifically in the context of the participants' experiences as individuals with either learning or physical disabilities. 2) While communication is just one facet of the variable engagement level, engagement level as a dependent variable was also not clearly stated in the article. In this particular variable, the measures through which communication was identified as such was not only restrictive, but are also limited or few in scope. Identifying engagement level of the self in terms only of rocking and hand-flicking are simple measures that do not cover the entirety of the measure, 'engagement level in terms of the self.' The article left the reader wondering whether the engagement levels were only identified in the terms reported by the authors, or whether there are other measures that they used to quantify engagement levels, and in effect, establish the quantitative relationship between engagement levels and response vis--vis the participant's immersion to hydrotherapeutic environment. In effect, what this observation demonstrates is that engagement level does not translated to communication only, b ut also an understanding of the activity and corresponding physical action that the individual has given in response to a specific communication prompt. 3) The article reported an increase in the engagement levels of the participants once they have been immersed or exposed to the hydrotherapeutic environment. Although there has been an increase in the engagement levels, three contentions to these findings can be observed. The first contention is that the reported increase in engagement levels are not reliable because of the questionable operationalization of the variables used for the study. Secondly, the study did not also report whether these increase in engagement levels are significant relationships or not. This is a crucial point that must be established in the article, since the increase in engagement levels of the participants will cease to be relevant and important if the reported percentages and increases are not significant in relation to the participants' immersion to the hydrotherapeutic environment. In effect, because the relationship established in the article were not clarified as whether significant or not, the effect and influence of the independent variable from the dependent variables loses its importance, rendering the study and its findings insignificant for the readers. 4) The design of the research study itself should have used a time-series experimental design, comparing the participants' performance during and after the time they have been exposed

Sunday, September 22, 2019

Hot Zone Book vs. Movie Essay Example for Free

Hot Zone Book vs. Movie Essay †¢In the book, we have Nancy and Jerry, and they are very important characters who deal with Ebola. Also they are married. In the movie, Sam and his ex-wife shares similar rolls like Nancy and Jerry. They try to stop the outbreak of Ebola virus in the monkey house. In the movie Sam and his ex-wife is divorced and still have problems between them. †¢movie changed Ebola to an Ebola-like virus called Motaba, the conditions of both diseases proved to be similar †¢The army took strong precautions in both cases, wearing Level 4 body-suits in the presence of the virus †¢They tried to contain a town and bomb it, and that made it so surreal that it eventually became difficult to take anything the movie says seriously. This made the movie fictional, and took away from the threat and danger of this deadly disease. †¢Robbie and Sam in the movie. It made it somewhat of a romantic love story †¢Daniels- equivalent to Jaaxs †¢movie didn’t focus on the monkey house at all †¢The pet store kind of took the place of the monkey house in that the host infected others at the pet store. †¢both have a laboratory monkey escaping from its cage †¢In the movie, the host monkey that was smuggled gets loose and threatens the lives of human race. In the book, one of the sick monkey in Reston escapes from its cage and Jerry spends days trying to catch it †¢similar is the potential rip in the space suits †¢Both Sammy Daniels and Jerry Jaax share a strong concern over his wife or ex-wife working with in the hot zone with the virus †¢Finally, the doctors in the book tried to help the villagers the best that they could, and eventually ended up leaving the village and the people behind. In the movie, the village, that had many people infected with the virus, was obliterated by a bomb †¢In movie, they catch the monkey responsible for everything

Saturday, September 21, 2019

SNPs of ABCG2 in Chinese Advanced NSCLC Patients

SNPs of ABCG2 in Chinese Advanced NSCLC Patients Introduction Lung cancer is one of the most prevalent and fatal malignant neoplasm all over the world and non-small-cell lung cancer (NSCLC) accounts for 80%–85% of all lung cancers(1). The majority of NSCLC patients, approximately 80%, presents in locally advanced (phase IIIA/B) or metastatic (phase IV) stages, which results in quite low 5-year survival rates, 8-14.1% for phase IIIA and 1-5% for phase IIIAB/IV (2). The standard treatment of advanced NSCLC, two-drug chemotherapy based on platinum, has reached a bottleneck with limited effect. Tyrosine kinase inhibitors (TKIs), a targeted drug of epidermal growth factor receptor (EGFR), have been recently introduced for the treatment of NSCLC. Clinical trials indicated that Gefitinib and Erlotinib treating advanced NSCLC patients with EGFR mutation could result a remission rate of 62.1%~84.6% and progression-free survival (PFS) of 8.4~13.1 months, which are significantly higher than that in chemotherapy group (32.2%~47.3% and 4.6~6.7 months , respectively), but not over survival(3-6). In order to implement accurate treatment of both chemotherapy and targeted therapy, it’s urgent to find other predictive targets of NSCLC patients to stratify for treatment. ATP binding cassette superfamily G member 2 (ABCG2), also known as breast cancer resistance protein, was demonstrated to be associated with the effect and prognosis of chemotherapy/targeted therapy in NSCLC (7-9). Because the single nucleotide polymorphisms (SNPs) of ABCG2 are supposed to affect the expression of ABCG2 protein and SNPs of ABCG2 in Asian population are different from other ethnicities (10), we conducted this study to evaluate the SNPs of ABCG2 in Chinese advanced NSCLC patients and its association with their prognosis of TKI therapy. Materials and methods Patients and treatment A total of 100 patients with pathology and cytology confirmed advanced or metastatic NSCLC were enrolled into this study between April 2012 and January 2014 in Hangzhou, China. The mutation of EGFR gene was assessable in 32 patients. Other patients were not assessed EGFR mutation. TKI targeted therapy was implemented in 70 NSCLC patients and other therapy was implemented in the other 30 patients. Patients with TKI targeted therapy were treated with Gefitnid (Astrazeneca pharmaceutical co., LTD) at a dose of 250 mg/day or Erlotinib (Roche pharmaceuticals co., LTD) at a dose of 150 mg/day or Icotinib (Zhejiang beida pharmaceutical co., LTD) at a dose of 375 mg/day. The patients’ characteristics were detailed in Table 1. All patients received chest CT every two months after 1 month of therapy. The efficacy of TKI therapy was clarified as complete response (CR), partial response (PR), stable disease (SD) and progression disease (PD) according to RECIST 1.1 [1]. Patients with CR or PR at more than 6 months were considered as responders. Patients with SD and PD at less than 6 months were considered as nonresponders.[A1] Progression-free survival (PFS) was defined as the duration from TKI therapy to disease progression. Overall survival (OS) was defined as the duration from diagnosis to death from any cause. All patients agreed to participate in this study and signed written informed consent. This study was approved by the Institutional Review Board of Nanjing Medical University and performed in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines[A2]. DNA extraction Blood samples were collected before chemotherapy and kept in a microcentrifuge tubes containing ethylenediamine tetra-acetic acid (EDTA). Genomic DNA was extracted using a DNA purification kit (Flexi Gene DNA Kit, Qiagen, Hilden, Germany). The concentration of genomic DNA was determined with NanoDrop 1000 (Thermo Scientific, Wilmington, USA) and then it was diluted to a standard of 25 ng/ÃŽ ¼l. Analysis of ABCG2 polymorphisms The ABCG2 34 G/A (dbSNP ID: rs2231137), 421 C/A (dbSNP ID: rs 2231142), 1143 C/T (dbSNP ID: rs2622604) and -15622 C/T (dbSNP ID: rs7699188) polymorphisms were amplified by PCR with the appropriate primers. The primers for PCR and single base extension (Table 2) were designed by the Sequenom Assay Designer 3.1 Software (San Diego, CA). The PCR reactions[A3] were performed at 95 °C for 2 min, followed by 40 cycles at 95 °C for 30 s, Tm for 30 s, and 72 °C for 60 s. After PCR amplification, single base extension reaction was performed following the method of Wiltshire et al [2]. Finally, polymorphisms of ABCG2 gene were tested and analyzed using matrix-assisted laser desorption/ionization timeof-flight mass spectrometry (MALDI-TOF MS) and Sequenom MassARRAY system (Sequenom, San Diego, CA, USA). Statistical analysis Allele frequencies of SNPs were calculated and their genotype distributions were assessed using Fisher’s exact test or chi-square test. PFS and OS were evaluated with censored survival time methods and 95% confidence intervals (CI) was obtained from multivariable logistic regression. Kaplan-Meier survival curves were plotted for OS and analyzed with log-rank test. All tests were performed 2-sided and a p-value were carried out using SPSS 18.0 (SPSS Inc., Chicago, IL, USA) software. Results ABCG2 gene polymorphisms The genotyping of ABCG2 34 G/A, 421 C/A, 1143 C/T and -15622 C/T were performed in all these 100 patients. For the ABCG2 34 G/A polymorphism, the frequencies of GG, GA and AA genotypes were 36%, 50% and 14%, respectively. The allele frequencies of G and A were 61% and 39%, respectively. The wide-type ABCG2 421 C/A genotype (CC) had a frequency of 53%, while the CA and AA genotypes were found in 43% and 4% of the patients, respectively. The allele frequencies of G and A were 74.5% and 25.5%, respectively. The frequencies of CC, CT and TT genotypes for ABCG2 1143 C/T were 66%, 29% and 5%, respectively. The allele frequencies of G and A were 80.5% and 19.5%, respectively. Regarding the ABCG2 -15622 C/T polymorphism, the TT genotype was observed in all patients. Therefore, polymorphism of ABCG2 -15622 C/T was not investigated in the following steps. Polymorphisms of ABCG2 and clinical characteristics Patients clinical characteristics were shown in Table 1, and the relationship between polymorphisms of ABCG2 and clinical characteristics were presented in Table 3. No significant correlations were found between ABCG2 polymorphisms (34 G/A, 421 C/A and 1143 C/T) and patients’ characteristics, including gender, age, smoking history, histology and EGFR mutation (p > 0.05). Although there was no significant relationship between ABCG2 421 C/A polymorphism and EGFR mutation, a trend that CA genotype was observed frequently in EGFR mutation positive patients (47.6% in positive patients vs. 18.2% in negative patients, p = 0.119). Then we calculated the allele frequency of A in these patients and a high frequency of allele A in positive patients (33.3% vs. 9.1%, p = 0.038) was observed. Polymorphisms of ABCG2 and clinical outcome of TKI The sensitivity of 70 patients to TKI treatment was shown in Table 4. NO significant correlation was found between ABCG2 polymorphisms (34 G/A, 421 C/A and 1143 C/T) and sensitivity (p > 0.05). As shown in Table 4, median PFS for carriers of the A-allele and GG genotype at position 34 of the ABCG2 gene who were treated with TKI therapy was 8.0 months (95% CI: 5.9-10.1, n = 45) and 6.5 months (95% CI: 4.1-8.9, n = 25), respectively. There was no significant difference in median PFS of NSCLC patients receiving TKI therapy between CC genotype and CA + AA genotype at position 421 of ABCG2 gene (p > 0.05). Median PFS of patients with CC genotype at position 1143 of ABCG2 gene was higher than those with CT and TT genotypes, but no significant difference was found (p > 0.05). The median OS of patients with ABCG2 34 G/A, 421 C/A, 1143 C/T polymorphisms was shown in Table 4. The median OS of patients with GG genotype at position 34 of the ABCG2 gene was 18 months (95% CI: 14.9-21.1, n = 25) and for those with other genotypes (GA and AA) was 31 months (95% CI: 22.9-39.1, n = 45). Figure 1 showed the Kaplan-Meier curve for OS for NSCLC patients receiving TKI therapy in relation to ABCG2 genotypes at 34 G/A (Figure 1A), 421 C/A (Figure 1B) and 1143 C/T (Figure 1C). There was significant difference between patients with GG genotype and those with GA + AA genotypes at position 34 of the ABCG2 gene (p difference between patients that were CC genotype regarding the position 421 of ABCG2 gene and carriers with other genotypes (CA + AA, p > 0.05). No significant difference was found in 1143 C/T polymorphism (p > 0.05). Discussion Our present study observed that three polymorphisms of ABCG2, 34G>A, 421C>A and 1143C>T occured more frequently compared with -15622C>T in Chinese advanced NSCLC patients. As for -15622C>T, all patients presented a TT genotype. Although no relationships were observed between different genotypes of ABCG2 polymorphisms and EGFR status, a higher frequency of allele A (421C>A) in EGFR mutation positive patients was observed. The other polymorphisms were not related to clinical characteristics. The sensitivity and PFS to TKI of 70 patients was not related to polymorphisms. However, the OS of patients with 34G>A mutant type (GA+AA) was significantly longer than those with wild type (GG). The ABCG2 protein is an important member of the ABC transporter superfamily, which has been suggested to be involved in multi-drug resistance (MDR) in cancer. Screening for SNPs in ethnically diverse subjects has identified more than 80 synonymous and nonsynonymous SNPs in the ABCG2 gene to date (12). The two most frequent polymorphisms identified were 34G>A (resulting in V12M) and 421C>A (resulting in a Q141K substitution) transitions (13). A novel diplotype of two polymorphic loci in the ABCG2 promoter involving -15622C>T and 1143C>T were identified recently (14). Introduction of other ABCG2 SNPs can be found in a recent review (15). Despite the similar allele frequency of 421C>A variant among East Asian populations including Chinese (34.2–35.0%) and Japanese (26.6–35.0%), the allele frequency is higher than that of Southeast Asians (15.0%), Middle Easterns (13.0%), Caucasians (8.7–12.0%) and African-Americans (2.3%) (10). Similarly, the allele frequency of the 34G>A variant in Chinese (20.0%), Koreans (19.8%) and Japanese (15.0-19.0%) is comparable. However, it is much lower than that in Southeast Asians (45%) and higher than other ethnic groups including Caucasian (1.7–10.3%), African-American (6.3%) and Middle Eastern (5.0%) populations (10). The allele frequency of 421C>A variant in our studied population was 25.5%, which was comparable to other Asian populations. However, the allele frequency of 34G>A variant was 39.0%, which was higher than other reports from Asian populations. We found that the allele frequency of 1143C>T variant and -15622C>T variant in our study was 19.5% and 100%, respectively. In Caucasians, it was reported to be 22% and 28%, respectively (16). We unexpectedly observed that all the included patients presented TT genotype of -15622C>T. As far as we known, this gene has not been investigated in other Asian populations. Future studies could be conducted to determine the polymorphism of -15622C>T in Asian po pulation and its potential impact. Physiologically, ABCG2 protein is highly expressed in the blood-brain barrier and gastrointestinal tract, where it is thought to play a role in protection against xenobiotic exposure. High ABCG2 expression has also been found in a variety of tumors and correlated with multidrug resistance and poorer clinical outcomes, as this transporter has the ability to extrude its drug substrates out of the cells, thereby decreasing their intracellular accumulation (17, 18)[16]. Primary structural variations of ABCG2 are associated with its drug-transporter function (15). Therefore, SNPs in the ABCG2 gene would influence the pharmacological effects differently in different patients. It has been demonstrated that 421C>A polymorphisms may express low amounts of ABCG2 (19-22) while the influence of 34G>A polymorphisms on ABCG2 expression remains controversial (22, 23). And regarding to 1143C>T and -15622C>T, some researchers found a decreased protein expression related to these two polymorphisms (21 ) and others found no relation between them (24). Moreover, 421C>A polymorphism has been demonstrated to be associated with ATPase activity and drug transport (18). Thus, several clinical studies have investigated the relation between ABCG2 polymorphism and clinical outcome of NSCLC. Mà ¼ller and colleagues (25) found that carriers of the ABCG2 421 A-allele treated with platinum-based drugs showed a significantly worse OS in all lung cancer patients. However, this effect was not statistically significant in the smaller subgroups of SCLC patients or NSCLC patients with platinum-based treatment. They did not found an association between 34G>A polymorphism and prognosis. Another study of 129 unresectable NSCLC cases treated with first-line platinum-based chemotherapy suggested that ABCG2 SNPs rs2725264 and rs4148149 were associated with OS (26). On the other side, there was also evidence showing that ABCG2 polymorphisms were not related to response or prognosis of NSCLC patients treated with gefitinib (24), erlotinib (27) and gemcitabine and/or platinum-based drugs and/or other drugs (28). In our present study, we found the OS of patients with 34G >A mutant type (GA+AA) was significantly longer than those with wild type (GG). However, we did not observe significant differences concerning other polymorphisms including 421C>A, which was found to be associated with prognosis of other cancer by other study (29). Interestingly, it was reported that ABCG2 34 GA/AA genotypes were associated with poor prognosis of Chinese patients with acute leukaemia (30). Polymorphisms of 34G>A seems to have an opposite impact in different types of cancer. The mechanisms are worthy to be investigated in future large studies. Moreover, ABCG2 SNPs was demonstrated not only related to TKI resistance, but also to TKI induced side effects. Cusatis and colleaguesinvestigated associations between allelic variants ofABCG2 with diarrhea and skin toxicity ingefitinib-treated patients. They found that 16 patients heterozygous forABCG2 421C>A developed diarrhea, versus only 13 (12%) of 108 patients homozygous for the wild-type sequence. However, this SNP was not associated with skin toxicity (28). A recent study found that patientscarrying anABCG2 -15622 TT genotype or harboring at least one TT copy in theABCG2 (1143CT, -15622CT) haplotype developed significantly more grade 2/3 diarrhea (23). In our present study, we did not perform the analysis on side effects. However, this is a serious concern which should be taken into consideration in future studies. In Conclusion, Our findings demonstrate a strong association between the ABCG2 34G>A polymorphism and the overall survival of NSCLC patients treated with TKIs, including Gefitnib, Erlotinib and Icotinib. Since these polymorphisms can be assessed with a simple blood test, it might potentially improve the stratification of patients for TKI treatment by identifying genetically high-response subgroups. Therefore, larger prospective trials are warranted to validate these findings. [A3]The PCR reactions were performed in 20 ÃŽ ¼l volumes on 384-well plates (cat. No. TF-0384/W, ABgene, USA) with 20 ng DNA, 10 pmol for each primer and 1 Ãâ€" PCR-Buffer (Sequenom, San Diego, CA, USA). à §Ã‚ ¼Ã‚ ºÃƒ ¤Ã‚ ¸Ã…“à ¨Ã‚ ¥Ã‚ ¿Ãƒ £Ã¢â€š ¬Ã¢â‚¬Å¡

Friday, September 20, 2019

Nature, the Environment and their Uses in Art

Nature, the Environment and their Uses in Art â€Å"I name that man an artist who creates forms†¦ I call that man a craftsman who reproduces forms.† Malraux is talking about artists and craftsmen, but might as well be talking about artists and designers. The audacity of the lowly â€Å"reproducers† was penalised by the iconoclasts, and perhaps we harbour the same fundamental suspicions about designers, people paid to build and sell us dreams just as frequently as they build and sell us houses. Yet it strikes me that there are two ways of dodging the suspicions of the public- the use of the imagination, and the use of Nature. If the two can be happily married then this superior union ought to germinate a magic all its own. â€Å"Moreover, a taste, not to say a passion, for building must be engrained in the child. Mechanical toys and mechanised entertainment kill his imagination and initiative; the feat of putting building blocks on top of each other hardly taxes the brain of a monkey† So the designer presents himself as a kind of sub-originator, and defers his symbolism to the greater origin. There is an individual and a more cosmic interest at work at the same time. The artist grows like a tree, developing, spreading, the ideas rising from the mysterious soils and falling like leaves. But the broader picture, a fluxing creative rhythm bridged by moments in time, demands a grander theory of unification. Nature is as synonymous with decay as it is with growth. The ephemera of modern life is as temporary, inevitable, immediate, as nature itself. Our cities have become sort of flaking, dying, layered forests, with their own dangers and rhythms of life and death. Everywhere we find reminders of our own impact on our surroundings- it is human nature, we cant help trying to clothe our hairless bodies and modify everything around us to make our lives more comfortable. But for some this seems to be a source of almost biblical guilt, and people go to extraordinary lengths, for their own reasons, to cover their tracks and paint their human presence out of the landscape altogether. Hundertwassers house in Vienna , and his designs for the â€Å"Eye Slit house† spring immediately to mind. Are we guilty enough to try to make our impact completely invisible? There can be no contention over the point that man has a negative impact on his environment and it may be that one solution is hiding mans impact altogether, (to enfold ourselves in natures arms, camouflaging ourselves in Her) while another might be to try to disguise our impact by turning our constructions into impersonations of Her. Is this really any different to the fearful icon building of ancient times, and do the â€Å"uglier†, modernist, construction-stating buildings represent a sort of iconoclasm- a return to buildings being made for human functionality rather than as a fearful acknowledgement of natures power as a constructor? Most of the architectural structures which are intended to resemble nature draw attention to the similarities between buildings and plants. Both are subject to a functional rhythm, both have access points, layers, a projectile dynamic- in other words, a sense of growth and promise. Yet plants are transcient, not concrete: they grow and bloom and fade and die, like people. They nourish and protect and reproduce and crumble away. The contrast with sturdy, permanent building materials used for, say, gothic cathedrals, Romanesque churches, the Eden Project, the Golden Gate Bridge, presents a sense of wonder and beauty in itself. Because plants are not like buildings. Buildings are sturdy and static and monumental. It is a fantastic thing to see a grand self-generating plant-beast made of concrete, it is alien and dreamlike and mesmerising but it is all these things because it is impossible. It enchants us because its beauty comes from a faraway, magical land, not from a world we know ab out but from one we would like to know- one in our dreams. Designs based on nature not only solve our problems, sate our yearnings and answer our questions, they also create new problems, new yearnings, and new questions. 1) Ecology since the 17th Century: historical relationships with Nature In the preface to â€Å"The Origins of form in Art†, Herbert Read references Henri Focillon, who suggested that life itself is a creator of forms, that theres no real distinction between art and life: â€Å"Life is form, and form is the modality of life. The relationships that bind forms together in nature cannot be pure chance, and what we call â€Å"Natural Life† is in effect a relationship between forms, so inexorable that without it this natural life could not exist. So it is with art†¦constitute an order for, and metaphor of, the entire universe.† Nature is uncontrollable and unpredictable- it is an ancient metaphor for uncontrollable intervention and for everything we cant accurately forecast. There is even an ancient Japanese treatise on archery which details the way in which the hardest part of the entire sport is waiting for the natural release of the string- a moment of serenity and detachment; total absence of striving. The flow of inspiration to the artist is analogous to this although it is unclear whether the creators inspiration rises from this or rises like it. Theorists have long been aware of this ambiguity and have thematised it themselves. Michael Fried interprets the woods, rocks and glens in Courbets paintings as faces or symbols or metaphors. Christopher Wood finds terrifying anthropomorphised trees looming over the subjects of Altdorfers exquisite scenes. The point is that those people who look at art, who are also interested in using it as an expression of themselves, consistently seek reflection in the pools provided by nature, natural imagery provides the perfect apparatus, somehow, for the admirer of human creativity to integrate the object into their own field of experience. When Paul Klee wrote that â€Å"The creation of a work of art is compared to the growth of a tree- its roots in the earth, crown in the air.† he is presenting an image of flow, as if an artist stands near the tree to allow the sap to rush in. This flow, though, occurs without conscious effort and the artist, crucially, experiences a transformation. â€Å" The idea that art is not a mirrored reflection of a given reality, but also a transformation of one element (which has its roots underground, in the unconscious) into another (made conscious in time and space). The artist is merely a channel whose function it is to transmit the forces of nature into forms of art.† Vivantes assessment that â€Å"art, far from being non-conscious, is a conquest of consciousness† is revealing, but wisely countered by Read, â€Å"Admittedly, the artists themselves may not always know when they are merely exploiting the unconscious, rather than â€Å"letting loose the riot of tender shoots†Ã¢â‚¬  As nature and art are so closely related, almost counter intuitively, so words and nature and words and art, are sometimes indistinguishable. All are concerned with abstraction, with roots, with origins, â€Å"we establish†¦our sense of reality by creating, for each experience, a clear and appropriate symbol- vocal sounds which were eventually stabilized as words. Every words was once an original work of art.† Whenever anything becomes too prevalent, too integrated into our consumer vocabulary, we scarcely notice it anymore and it loses its impact. In becoming part of our environment, ourselves, the clichà © ceases to become something desirous to us. Designed solutions respond to an expression of specific desire or need, and so become a meta expression of the same need. While design solutions sate specific hungers, art is an expression, and not even necessarily a resolution of, thematic desires. Poetry and the visual arts dance around the clichà © while occasionally retaining originality (Poussins Dance to the Music of Time is a delightfully literal example of this)- art finds a janus-faced simultaneity, a place for both the clichà © of nature and the pure artistic drive of â€Å"artisticness†. Design, however, is trapped in the problem solving one-dimensional rationality of the prevailing zeitgeist. Perhaps nature is a way of side-stepping the clichà ©, but it can also present itself, maddeningly indistinguishably, as the alluring siren. Maybe there is a link between the mechanised production of imagery and forms and the predominance of natural imagery in the products and lifestyles consumed by people nowadays. There could well be a relationship, yet unexplored, between the unnatural production of natural images and the homogeneity of the images themselves. If the origins are authentic and essential then we should expect products to be more persuasive, more reflective of their origins, more transparent. Mechanisation has allowed for imagery to â€Å"ride the zeitgeist† and generate a new kind of language of â€Å"natural† iconography- perhaps where once there was religious iconography. In Poussins Dance to the Music of Time we find Arcadia, the natural utopia, being equated to male/female synthesis, and then, on another level, the gender synthesis standing for a synthesis of heaven and earth in the familiar conceit of rhythm. In Peter Blakes extraordinary work, The Arcadian Cipher pentagram shapes are located everywhere as a kind of unification symbol: Blake is anxious to synthesise traditionally opposing forces, and make sense of illogical harmonies through the imposition (or uncovering, in his terms) of this particular hypograph. His choice of symbol is less important than his- and other academic semiosticians impulse towards holism. I have already suggested that artists are involved in a janus headed effort: always trying to channel pure nature and represent her in a familiar language- to experience and the represent the clichà © at once. Blakes assessment of the Dance describes the duplicity: â€Å"For where the other two pentagrams represent the Jesus figure and Pan, this definitely connects them with a female element. Through it we are able to establish a male/female partnership both in heaven and on Earth and between heaven and Earth, and it is one which symbolises the poles upon which the Earth spins. The painting depicts Hermes playing his lyre – music was his method of communication between two worlds- and a group of earthly figures dancing to his celestial tune. On the left hand side of the work is a column on which is mounted a carving†¦of two heads facing away from each other.† Theory of this sort, while certainly in constant danger of toppling into quasi-science, superbly exemplifies the inextricability of Nature and Geometry. Theories of Arcadia are saturated with geometric semiotics; art writers constantly trace and re-trace paintings, covering them in layers and layers of â€Å"mathematical† justification. Whether any of these theories have any real use or even make any sense outside of their own self-imposed rules is not my point. I am interested in the relationship between the powers of nature and the powers of men, the irresistible urge to explain the mysteries of nature, her circadian rhythms, her life giving and life stealing properties, her silent chthonic swell and the threat and awe experienced by the bewildered humans that observe her. As one of the most evocative and symbolically potent plants on the planet, the cactus has played many roles in South American tradition and folklore. As with any hostile climate, indigenous species that seem to offer solace will inevitably acquire mystical significance as the protection they offer is associated with promise. To the parched population of parched landscapes, cacti are life-giving, life-saving, surprising, mysterious, frightening- divine. Cacti started off on American continents, and are still most associated with these places- but they have experienced a massive geographical distribution over the centuries, and cacti have been able to instigate habitats around the world. One rumour says that Christopher Columbus was the first person to have taken the first cactus to Europe, presenting this peculiar plant to Queen Isabella of Spain, however this is of course apocryphal. During their explorations on the American continents, the Spanish Conquistadors found, among many other things, these strange vision inducing plants that were utilised ceremonially by the natives as a religious sacrament and was revered as virtual gods. The native South American name for their spineless dense-shaped cactus (Lophophora Williamsii) was peyoti. It is a plant native to Mexican and south west US with button like tubercles which may be eaten fresh or dried as a narcotic. Initially, Cacti (peyoti) were employed for healing purposes, for attempting to divine the future and for generating hallucinogenic visions during scared rites. Although these hallucinations often appear to be compared to LSD trips, the peyote â€Å"acid† is 4000 times less potent, only briefly affecting the chemical balance and activity of the brain. The Spanish chronicler, Fray Bernardino de Sahagun, claimed that natives used a certain plant to induce hallucinatory state and estimated that peyote was widely used at least 1890 years before the arrival of Europeans. The earliest European record dates from around 1635 with the first column of Historia de las Indias Occidentales by Gonzalo Hernandez de Oviedo y Valdes appeared with illustrations of what we would now classify as Cereus and Opuntia. In 1886 that the German pharmacologist, Louis Lewin, published the first systematic study of the cactus, to which his own name was subsequently given- Anhalonium lewinii. The cactus was already well known and loved by primitive religions and the Indians of Mexico and the American Southwest. One of the early Spanish visitors to the New World wrote, they eat a root which they call peyote, and which they venerate as though it were a deity. It became clear why this plant was venerated as a god, when such eminent psychologists as Jaensch, Havelock Ellis and Weir Mitchell began their experiments with mescalin, the active principle of peyote. Mescalin research has continued, and now chemists have not only isolated the alkaloid; they have learned how to synthesize it, so that the supply no longer depends on the sparse and infrequent crop of desert cacti. Neurologists and physiologists have spent years investigating the mechanism of mescalins action upon the central nervous system, and at everyone from philosophers to writers- notably Aldous Huxley- have taken mescalin in the hope that this mystical cactus extract may shed some light on such ancient, unsolved riddles as the place of mind in nature and the relationship between brain and consciousness. It is surely no coincidence that the peyote cactus, so ubiquitous, so loved and feared, is also identified as the solution to ancient problems of human displacement. We identify with the cactus perhaps. It projects intelligently, like an alien from the sand, while we wonder how we are supposed to best relate to our surroundings. When we look at the cactus we see ourselves done better. If anything on the planet holds the key to mans reconciliation with his estranged mother nature, it is surely the cactus. It is too alien to be part of our problem, we reason, so it must be part of the solution. 2) Taoism and Nature â€Å"Humans model themselves on earth, Earth on heaven, Heaven on the Way, And the way on that which is naturally so.† Lao Tse Daodejing (Tao te ching) #251 This simple but sententious dictum was delivered by an Chinese ancient sage, Lao Tse, the founder of Taoism. The saying suggests a means of building a harmonious relationship between beings and nature. Taoist ideas about conservation and ecology, with nature as the inspiration and conclusion to all things, reflect and resemble new philosophies of industrial design, to some extent. Alongside Buddhism and Confucianism, Taoism is one of the three great religions of China. It can be roughly translated into English as â€Å"path†, or â€Å"the way†- that is, the way of correspondence between man and nature, and the way that is a kind of path of nature the course of natural world. The term Tao describes a power that envelops and flows through all things, both living and nonliving. As such, it serves to regulate natural processes and encourage a cosmic balance of all things in the Universe. Tao suggests that the answers to lifes problems can be found through inner meditation and outer observation. Taoist ideas and images may have nurtured or inspired a love of nature in the Chinese, so that they have traditional felt a need to protect it, and have had many ways of cultivating an affinity with it. The Chinese have always seen nature as a companion, a place of security and support to which they could retreat from the cares of the world to rest or heal themselves. Nature, through Tao, is also sincerely life-affirming. Nature can be unfathomably brutal and Tao constantly reminds that the external world is explicitly on-ideal: in fact, according to Tao, the ideal world can only be found through a spiritual path. The only thing that might compromise ones eternal happiness, in Tao as in Buddhism, was a state of mind, an attitude. Both Tao and Nature are associated with a non-materialistic attitude to life, a spiritual approach to living which many perceive as a possible answer to the social issues of today: the problems of sustaining a unified and healthy social order. Taoists believe their religion holds the answers, as it advises its followers to emulate nature, with its simplicity and relaxed, non-intellectual approach to life. Tao seems to suggest that many of the environmental problems of today have arisen from a materialistic human attitude that has overwhelmed mans spiritual relationship with his natural environment. Rather than coexisting with our living space, people have begun challenging it, and it has even become a respectable achievement to be seen to â€Å"conquer† nature. An estimated 42 million acres of tropical rainforest are destroyed annually, an area the size of Washington State. Around 50,000 species of plants and animals are condemned to extinction every year, an average of about 140 species a day. There are more people than ever, and these people routinely pillage resources, destroy or change natural processes arbitrarily and are support the production of thousands of products that lead towards the destructive path of the environment – contradicting the Taoist path. Increasingly materialist in their lifestyles, most people believe that only matter exists, leaving no room for spiritual beliefs. Our quest for pleasure corresponds to a demand placed on the Earth for immediate gain. The visible world takes precedence over any spiritual or psychological activities and ultimately a form of materialism becomes the only truth and belief. Natures force is unknowable in its essence but observable in its manifestations. With the crisis of energy a nd resources, the crisis of ecology and environment, the crisis of belief and mortality we experience force in the form of natures lamenting reactions. We believe in the formless and eternal Tao, and we recognize all personified deities as being mere human constructs. We reject hatred, intolerance, and unnecessary violence, and embrace harmony, love and learning, as we are taught by Nature. We place our trust and our lives in the Tao, which we may live in peace and balance with the Universe, both in this mortal life and beyond. Creed of the Western Reform Taoist Congregation The recent revival of instinctive desires preserve the health of our planets life without compromising human comfort is the task of ecological attitudes in art and design. Those ecological design solutions that take on board Taoist philosophies link nature, culture, and technology to resituate social human requirements in an environment where the balance of nature receives precedence. Artists and designers must of course work within the constraints imposed by their clients, including the practical and material demands made by every stage of production. Classical Taoist philosophy, formulated in part by Laozi (the Old Master, 5th century B.C.), in part by the editor of the Daodejing (Classic of the Way and its Power), and in part by Zhuangzi (3rd century B.C.), represented a reinterpretation and development of an ancient nameless tradition of nature worship and divination. Laozi and Zhuangzi, living at a time of social disorder and great religious skepticism developed the notion of the Dao (Tao way, or path) as the origin of all creation and the force unknowable in its essence but observable in its manifestation that underlies the mechanisms of the natural world. These men saw in Dao, Nature, and in Nature, Dao. In both these Ways lay the secret to harmonious living. According to these early teachers, the order and harmony of nature was a model for human structures, so much more stable and enduring than either the power of the state or the civilized institutions constructed by human learning. The early Taoists taught the art of li ving and surviving by conforming with the natural way of things; they called their approach to action wuwei (wu-wei lit. no-action), action modelled on nature. As one writer explains, â€Å"Their sages were wise, but not in the way the Confucian teacher was wise, learned and a moral paragon. Zhuangzis sages were often artisans, butchers or woodcarvers. The lowly artisans understood the secret of art and the art of living. To be skillful and creative, they had to have inner spiritual concentration and put aside concern with externals, such as monetary rewards, fame, and praise. Art, like life, followed the creative path of nature, not the values of human society.† Chinese history is dense with stories of people who have grown tired of the pretensions and desperation of social activism increasingly aware of the fragility of human achievements, and whose response has been to retire from the world and turn to nature. Such people have traditionally retreated to a countryside or mountain setting to commune with natural beauty, often composing poetry about nature , or painting interpretations of the scenes surrounding them, as they attempted to capture the creative forces at the heart of Natures vitality. Such people might share their excursions with friends or family, drinking a bite of wine, enjoying the autumn leaves or the evening skies. The literature of Chinese utopians often had a Taoist slant: Tao Qians famous Peach Blossom Spring told of a fisherman who happened across an idyllic Chinese community who had fled a war-torn land centuries earlier, and lived in perfect simplicity and harmony ever since, blissfully oblivious to the turmoil of history beyond their idyll. While the inhabitants urged him to stay, the fisherman departed and shared his discovery with a local official. However hard he tried, he never found a path back to the grove. The fisherman never found a route back because he had failed to understand that he had discovered an abstracted, ideal, world – and one which was to be found not via an external path, but a spiritual one. The utopia was a state of mind, a unique attitude. Laozi and Zhuangzi had reinterpreted nature worship and belief in esoteric â€Å"magical† arts as something both more abstract and more tangible, but the ancient methods and beliefs crept back into the tradition as ways of using knowledge of the Dao to enhance and prolong life. Despite its pragmatism, for some Taoism would always go hand in hand with magical belief. Some Taoists poured their energies into a search for isles of the immortals, or for herbs that could unlock the secrets of immortal life. Many Taoists were interested in health and carried out many studies of herbal medicine and pharmacology, in fact entailing significant advancements in these arts. Taoists even worked out the principles of macrobiotic cooking and other supposedly new and healthy diets. Sensitive to natural processes, they recorded gymnastic mechanisms and studied the effects of massage on keeping the body strong and youthful. Taoists were, then, both magicians and of proto-scientists: they represented the sector of Chinese culture that most closely studied and communed with nature. Some Taoists held that nature was filled with spirits however, theosophically, such spirits were simply many manifestations of the one Dao, something impossible to represent as a single image or in one discreet form. â€Å"The Tao of Heaven operates mysteriously and secretly ; it has no fixed shape; it follows no definite rules; it is so great that you can never come to the end of it, it is so deep that you can never fathom it.† The Huai Nau Tzu The central theme of Taoism is a relationship, and as such contradicts the general western attitude to nature. Nature should not be considered as something passive, awaiting mans masterful control, but as an equal or even superior partner be mastered in a relationship. The aim of the Taiost is to rediscover and eventually merge with the ordered origin of the universe and the only way to do so is the Tao – the path shown to us by nature. Early Taoist philosophers set out from their civilised worlds to take expeditions into the natural world, where they hoped to learn from primitive people living in remote mountain villages. Initially they aimed to introduce the benefits of human civilization to the mysteriously rhythmed order of nature. According to the Tao, nature is â€Å"infinitely wise, infinitely complex, and infinitely irrational. One must take a yielding stance and abandon all intellectual preconceptions. The goal is wu wei, doing nothing contrary to nature. Nature does not need to be perfected or improved. It is we who need to change; we need to come into accord.† Contrary to one possible interpretation of Yin/Yang, Taoists rejected all dichotomies, including the fundamental existence/non existence one, since it is their belief that both stem from the same source, â€Å"Athe deep and the profound. Rather, Taoisms goal is to use consciousness of duality and wisdom about it to reach the stage before any dualities existed. There is only one path to this source, then – the observation of nature. As one writer explains, â€Å"The Tao is a divine chaos, not a random accident. It is fertile, undifferentiated, and teeming with unrealized creation. It is the mother of everything in nature; it is a great darkness that operates spontaneously to give birth and life to all things.† 3) Ecological thinking in contemporary art and design Are we really moving towards a common lexicon of human creation and natural creation? Alan Power cites Steiners â€Å"startling prediction†, â€Å" Buildings will begin to speak. They will speak a language of which people have as yet not even an inkling,† Yet I wonder how startling this really is. Buildings are indeed more â€Å"scientific†, more complex with less obvious evidence of human intervention. Many buildings nowadays appear to have been designed and built by aliens, no longer made to be lived in but impenetrable to our rational human minds. Again, they resemble complex organisms in their initially baffling structure, their illogical shapes and apparent preference of shape and form to practicality. But they are still made by humans, albeit humans employing a dozen layers of technology to translate abstract geometry into audaciously confusing formulae. They are still constructed by and for humans to use, and to that extent are utterly comprehensible, at least to the humans that use them. Where there is room for gratuitous aesthetic treatment in a design, designers, consciously or not, grasp the zeitgeist, construct from fashionable and available materials, and exploit their artistic freedom as far as their unconscious n otions of the â€Å"aesthetic† will allow them to. These notions, I am attempting to argue, are controlled by biologically ingrained forms of the organic. It doesnt matter if a building is technically accomplished to exhibit skeletal forms, as with the giant domes of the Eden Complex in Cornwall, the Brooklyn Bridge in New York and the Mildred Cooper chapel in Arkansas or swollen like the pregnant belly of the Guggenheim, NY . Nature can be found in all design, both rational and irrational, and the more we try to escape it, to avoid mimicking it, the more we are forced to study its base rules, its gravity and its ebb and flow, the tensile strength of its spider-webs, the effects of its uncontrollable eruptions and tidal waves and tornados. Nature is absolutely full of potential metaphors for ways in which we can improve our lives. Today, apple peels are being used by scientists at the University of Clemson as a metaphor for edible packages disolvable pouches like boil in the bags that add protein to a macaroni and cheese dinner, or packages that act as a booster for laundry detergent. Theres certainly a human instinct to perceive products inspired in obvious ways by nature, as being somehow â€Å"good† for us, or â€Å"good† in a moral sense. Of course, human instincts are not to be trusted blindly, and it doesnt follow that because a kind of packaging is inspired by an apple core it is environmentally friendly, inspirational, beautiful, or better for us or the world. But I suppose it has a slightly higher chance of being one or more of these things, our instincts are not too wide of the mark and do control the things we want to buy and sell. A study entitled â€Å"Trees in Small City Business Districts: Comparing Responses of Residents Potential Visitors† begins, â€Å"This study tested whether public response to trees in the downtown business districts of smaller cities is comparable. Research methods included interviews and mail-out surveys. Survey respondents prefer having large trees in retail streetscapes. Trees are also associated with reported increases in patronage behavior (such as travel distance and visit frequency), and willingness to pay more for products. Few differences in response were detected between small city residents and potential visitors who reside in large cities.† What is it about natural organisms that make us want to part with our money? Marketing strategies state such things as fact, using careful example to â€Å"prove† what we â€Å"intuitively† want to believe is true that â€Å"good product and package designers have known for centuries- that the best inspiration for new products comes from nature. The camera mimics the human eye. Helicopters, like hummingbirds, can hover and fly backwards. Velcro brand fasteners were inspired by prickily burrs attached to a Scottish inventors boot.† They get away with this because nature is, and has always been, such an alien force to us humans, as we have seen. Like an alien from another planets, we hope it will be benevolent and, through its own irrepressible character, its mysterious and enviable immortality, hold the secrets to our own improved lifestyles and lifespans. Of course our relationship with nature has changed slightly as we have changed, as a race, but our view of H er remains essentially the same as ever. We still need to imitate and control what we see outside us, in the hope that we can sypher off a little of the magic and mystery for ourselves. In the developed world these harmless, yet irrepressible rhythms are increasingly invisible. It is possible to spend months in a city dwelling, never seeing a dead animal, a nesting bird, a tree in blossom. Nature has become more promising, more mysterious, more magical, and more frightening through its real invisibility, but nature is not wilfully elusive or coy, this is an invisibility we that have imposed. Inevitably, the packages and products that are environmentally superior that are kind to nature also resemble it: they might be inherently efficient, easily recycable, and often they use recycled materials made from renewable resources. One organisation creating such products, back in their 1990s heyday, was â€Å"Zerosm†, and they identified several techniques fo

Thursday, September 19, 2019

Lord Of The Flies :: essays research papers

SettingThe story takes place on an island somewhere in the ocean. The island is described by the author as tropical and boat shaped. Along the coast there are sandy beaches followed by a variety of vegetation and "creepers". There are also the orchards, which rise up to the treeless and rocky and rugged mountain ridge which extends out of the ocean. Judging from the predicament and dialogue in this story the date in which it takes place is probably the mid 1900's during World War II. The mood created in this story is very complex and rapidly changing. It changes from that of a scary, recessive mood to a light, and cheery one. The way in which the story is written the mood can change literally from chapter to chapter. In the beginning it starts out light and happy and as the novel progresses and the boys start to battle, it starts to become dark and savage.CharactersJack is red-headed and thin he is also introduced as the leader of the boys' choir. To his dismay he loses the election for leader and he becomes the head hunter and is also in charge of maintaining the signal fire. As the story progresses he and his hunters begin to "slack-off" and abandon their duties in caring for the fire. In the end Jack and his hunters leave Ralph and start their own tribe on the rocky side of the island.Ralph is a tall, blond and is one of the oldest boys on the island. In the beginning of the story he is pictured as the leader of the boys when he blows the conch shell to call the first assembly. During the course of the story he tries to maintain the structure of their civilization and is continually forced to compete with Jack for approval from the boys.Piggy is a fat, asthmatic boy with bad vision. Throughout the story his weaknesses are preyed upon by the other boys much like that of the "pigs" on the island, thus the name. But despite his appearance, Ralph begins to depend upon Piggy for intellectual and spiritual guidance. Do to his vision, Piggy had unusually thick glasses, which was a benefit to the others on the island, and aided in the lighting of the signal fire and in the roasting of the pigs.Simon was a skinny, silent boy with black hair.

Wednesday, September 18, 2019

Effects of Underage Drinking on Society Essay -- Alcohol Regulation, Y

Underage Drinking Anyone who is below eighteen years of age is considered as underage and laws in many countries prohibit such a person from consuming alcohol. Alcohol happens to be the most commonly abused drug not only among the youth but also among adults. This paper explores underage drinking, its effects on the society and outlines what can be done to curb it. Young people are considered to constitute the largest number of alcohol consumers and they account for a large portion of alcohol sales. This is despite the strict drinking laws that govern many countries as regards alcohol purchase and consumption. Underage drinking, which has been on the increase, is allegedly the major cause of alcohol-related problems facing the modern society. The most severe effects of adolescent drinking include drunk driving that leads to accidents and even death, violence, poor performance in school, addiction, poor relationships and damage on adolescent brain development among others (Bonnie and O’Connell 58). The society is to a great extent affected by these effects through deaths and lost productivity among the youth. This has become a challenge to the society and government, which has been accused of doing nothing about this menace. Weak personal character, bad social states and poor cultural settings are some of the major factors that are belie ved to be behind underage drinking. Bad character among adolescents is a major factor behind underage drinking and it is caused by the personal beliefs and attitudes of the young adults towards alcohol, defiance, low commitment towards personal objectives and undue interpretation of freedom (Komro and Toomey 2). The lack of principles and autonomy, which help the youth to say no to illicit beh... ...wn to a personal decision on whether one should or should not consume it as others will still do even if all these interventions were to be put in place. The strategies above can therefore not guarantee an end to underage drinking but they can give significant and sustained reduction in adolescent drinking if efficiently implemented. Works Cited Bonnie, Richard J., Mary Ellen O’Connell, and National Research Council (U.S). Reducing Underage Drinking: A Collective Responsibility. Washington, DC: National Academic Press, 2004. Print. Ellul, Duncan Aaron Borg. Risk Perception, Awareness and Prevention Measures to Reduce Underage Drinking and the Illegal Purchase of Alcohol in Malta. Boca Raton, FL: Universal Publishers, 2005. Print. Komro, Kelli A., and Traci L. Toomey. â€Å"Strategies to Prevent Underage Drinking.† The News. 19 Jan. 2011: 1-29. Print.

Tuesday, September 17, 2019

Agenda Setting Theory – Introduction

Introduction Agenda Setting Theory is first developed by Professor Maxwell McCombs  and  Professor Donald Shaw  in their  Chapel Hill study  in 1968. The agenda setting theory is separate into three parts which is media agenda, public agenda and policy agenda. Agenda setting theory is defined as the power of news media whereby mass media set an agenda which will influences the public which is called as public agenda by highlighting the issue frequently in media. Therefore the main effect of media in agenda setting is telling people not what to think, but what to think of.The policy agenda is the issues that policy makers consider important after the public start to make campaign or petition to show protest against the organizations. Mass Communication plays an important role in our society its purpose is to inform the public about current and past events. Mass communication is defined in â€Å"Mass Media, Mass Culture† as the process whereby professional communicator s use technological devices to share messages over great distances to influence large audiences.Within this process the media, which can be a newspaper, a book and television, takes control of the information we see or hear. The media then uses gate keeping  and agenda setting to â€Å"control our access to news, information, and  entertainment† (Wilson 14). Gate keeping is a series of checkpoints  that the news has to go through before it gets to the public. Through this process many people have to  decide whether  or not the news  is to be seen or heard. Some gatekeepers might include reporters, writers, and  editors. After gate keeping comes  agenda setting. Elaboration of the TheoryThe Agenda-Setting Theory says the media (mainly the news media) aren’t always successful at telling us what to think, but they are quite successful at telling us what to think about. The power of news media is to set a nation’s agenda, to focus public attention on a few key public issues, is an immense and well-documented influence. For example, newspapers provide a host of cues about the salience of the topics in daily news. They will lead story on first page, large headlines and etc. Besides that, television also consider as a mass communication tool.Television offers numerous cues about salience too. Their opening story is on newscast, length of time devoted to the story and etc. As said by Walter Lippmann, Agenda-Setting Theory is â€Å"the world outside & the pictures in our heads†. The news media are a primary source of those pictures in our heads about the larger world of public affairs, a world that for most citizens is â€Å"out of reach, out of sight, out of mind. † Agenda setting is divided into two levels where the first level stress on common subject that media thinks the subject is important.The second level decides which part of the subject is important. Both level leads to the concept of agenda setting where the concept is divided into three parts. The first part of the process is the importance of the issues that are going to be discussed in the media. Second, the issues discussed in the media have an impact over the way the public thinks, this is referred as public agenda. Ultimately the public agenda influences the policy agenda. Furthermore, the media agenda affects the public agenda, and the public agenda affects the policy agenda.People would attend only to news and views that didn’t threaten their established beliefs. Agenda-setting will reconfirms the power of the press while still maintaining that individuals were free to choose. The agenda-setting function is a 3 part-process. Firstly, media agenda is the issues discussed in the media. Secondly, public agenda means issues discussed and personally relevant to public. Lastly, policy agenda is the issues that policy makers consider important. Media agenda and public agenda are close to each other. Media agenda is the set of i ssue addressed by media sources.It is a composite index of media prominence reveled the importance of foreign policy, law and order, fiscal policy, public welfare and civil rights. While public agenda are issues the public consider important. It is the rank of the five issues was identical to the media agenda. The key concept and terms are agenda setting, salience transfer, gatekeeping, framing, priming and determinants of agenda-setting effects. Agenda setting is giving priorities to alternative policy issues but in the early communications studies, shown a mixture about the ability to influence public opinion on the given issue.Salience transfer refers to the capacity of the media to influence the relative importance individuals attached to the policy. Next is gate keeping is a process that control the media content. Framing is the importance and interpretation of people attach to potential items on the public agenda are strongly influenced by how the media present news stories. P riming happen when framing centers on political loading of the presentation of news, it can be conscious and not conscious. Priming basically mean draw attention to certain issue even in a neutral manner. Last but not least is the determinant of agenda-setting effects.Media credibility or also known as media reliance are found that the determinant is weaker than the media exposure and media exposure are more important than media credibility in relation to presidential state of the union addresses. Application of the Theory In Malaysia, one of the case studies was to examine the Malay language newspaper’s media agenda during the general election. (Ahmad Zahid Hamidi, UPM) The study was conducted to examine the use of the Barisan Nasional (BN) manifesto as the media agenda during the general election for the year 1982, 1986, 1990, 1995 and 1999.A model for the study was constructed based on the Agenda Setting Theory. A content analysis was conducted on 50 issues of Utusan Malay sia (UM) and Berita Harian (BH). Throughout the studies, it was found that there were 11 major themes frequently used in the BN manifesto namely: politics, foreign policy, development, economy, social education, security, religion, workers welfare, agriculture and the quality of life. Above were the main themes in the news during the general election for the year of study.The content analysis also found that there were 4461 news with the BN manifesto shown in 11 major news themes with â€Å"politics† in the lead and the â€Å"quality of life† ending the list. It also showed that the BN manifesto was mainly covered in various sections such as the Local News, Foreign News, Special Column, Main Column, Editorial, Advertisement, Economy, Asean, Forum, Articles and others. While the coverage on News, Articles, Photographs, Editorial, Letter to the Editor, Cartoon, Columnist and Comments also showed the present of BN manifesto.There was also a small difference between the tw o newspapers in terms of its news coverage on the BN manifesto during the general election. The study clearly showed that the media agenda of the two mainstream newspapers in the country was framed by the content of the BN manifesto during the duration of the general election for the year 1982, 1986, 1990, 1995 and 1999 and thus, strengthening the Agenda Setting Theory. The media institution and politic institution are closely linked to each other and are hardly being separated. Both the institutions are interdependent on each other.In Malaysia, we are practicing the democracy system, thus, media are an important instrument to achieve the democracy level; Media play a role in influencing the public in deciding their votes during a general election, either to vote for the specific individual or the party. Besides, media also take control in the politic process as mentioned earlier in the Agenda Setting Theory. In a democratic country like Malaysia, the process in politics often invol ve media as a tool to spread the news on certain parties’ issues and frame some of the suggestions or views on certain parties or individuals.In order to achieve a country that is practicing democratic system, the general elections were often used as a measurement tool in testing the level of support among the voters toward a specific party. Personal experience & interpersonal communication among elites and other individuals So, the process of general election in Malaysia is a very crucial component in a democratic way. There were 12 general elections being held so far in Malaysia which were in the year 1959, 1964, 1969, 1974, 1978, 1982, 1986, 1990, 1995, 1999 and 2004.Also, there were 6 Prime Ministers that have involved themselves in became the main politic communicators in every general election that have been done. Every Prime Minister has their own plans in collaboration with the media to enhance their communication through media, and utilized it in a proper ways. Gatek eepers’ influential media & spectacular news & events Policy Agenda Public Agenda Media Agenda Real world indications of the importance of an agenda, issue or event Figure 1: Three Main Components in Agenda Setting ProcessIn political communication, media is one of the aspects to be deal with. Others include media agenda, public agenda and policy agenda. All these three main components form a process (Agenda Setting Process) by which a complete political communication is carried out where the media were used to disseminate the messages or information to mass audiences. This process is involved in the Agenda Setting Process and has TWO levels: The media agenda affects the public agenda, and the public agenda affects the policy agenda.The communication using media has done by the politicians to publish their views and news or in this case, the manifesto of Barisan Nasional in Utusan Melaysia and Barita Harian in the media agenda. However, there are existence of gatekeepers that may influence the news and events to be published. In the case studies on BN manifesto, the gatekeepers here would be the editor and the owner of Utusan Malaysia and Berita Harian newspapers publishers.The purposes of having gatekeepers here is to avoid harmful, negative, sensitive or religious issues being discussed which may cause misunderstanding within the nation According to the research, Utusan Malaysia and Berita Harian used media agenda to influence the public, and this has brought the issue to a broader step which is the public agenda, where the public start discussing about the issue. In the case studies, there are some similarities in the manifesto of Barisan Nasional.During the general election, extensive media coverage on the political issues of BN were published continuously especially in the front page of the newspapers being analyzed: Utusan Malaysia and Berita Harian. Those issues are similar to the manifesto of BN. Therefore, the public can gain most of the inform ation about BN from the newspaper than the other party. After the public has start discussing about the issue, which is the involvement of BN’s manifesto in both the newspapers being mentioned, there were some activists who tried to support or banned the manifesto.The real world indicator will decide the importance of the agenda itself. Then, through the personal experiences and interpersonal communications among the elites and other individuals, there might be changes in the policy agenda. Finally, the policy agenda causes the media agenda to publish about the news and information all over again. The Agenda Setting Process will be repeated. ————————————————- Strengths and Weakness of the Theory We found that agenda setting theory has three strengths. First, agenda setting theory has explanatory power.Because this theory explains why most of the people prioritize th e same issues as important. Therefore, most of the people will discuss the same issues at the same time. They will also concentrate discuss the issues because they think that the issues are affecting them. Second, this theory also has predictive power as it predicts that if people are exposed to the same media, they will feel the same issues as important. For example, if one issue be the headline of all the newspapers for one week, people will feel that this issue is very important and it will affect their life.Furthermore, this theory has organizing power because it helps organize existing knowledge of media effects. There are also weaknesses, such as media users may not be as ideal as the theory assumes. People may not be well-informed, deeply engaged in public affairs, thoughtful and skeptical. Media just tell them what to think about the issues. People just know the appearance of the issues and not deeply engage in the issues. They will also think that are the issues reported co rrect or the media have hide something bad that they do not know about the issues.So, some of the people do not trust what the media have said. Instead, people may pay only casual and intermittent attention to public affairs and remain ignorant of the details. For people who have made up their minds, the effect is weakened. News media cannot create or conceal problems; they may only alter the awareness, priorities and salience people attached to a set of problems. Research has largely been inconclusive in establishing a casual relationship between public salience and media coverage. Suggestions to Improve on the TheoryFor communication theory to be adopted by researchers and remain viable, it must be able to survive and grow through its ability to adapt to changing environments, encourage further research, and serve as a foundation for studies beyond those in which the founders originally applied their theory. According to McCombs and Shaw (1972) the result of their study shows that fewer voters knew about specific issues. While they found out that media were often effective in raising awareness of issues with undecided voters.They also found that issues presented by media that were new to audiences were better received by the public than issues with which the public was already familiar. The key factor to the ability of media to have an agenda-setting effect upon their audiences depends on the desire of the viewers to become informed about the issues. For example, when the voters wants to know more about their ideal government leaders the public have to search for more information about the leaders and the party as the desired for them to become informed on the issues instills a strong motivation factors for the public’s.Although the theory may seem to be acceptable but the theory still have its own weaknesses and failure which are visible and need to be improved. For example, while the article concentrate on the presentation of the issues during the e lection campaigns, the willingness of voters to listen to issues presented by the media, they fail to examine the degree to which mass media is able to raise issues and attract information-seeking audiences on its own but they fail to examine the degree of how the mass media is able to heightened public interest of political issues during election seasons to perform an agenda-setting function.Besides that, the media agenda in agenda-setting theory have their own limitations, as media may not be as ideal as the theory assumes. The information from the media may not deliver appropriately, deeply engaged in public affairs, thoughtful and skeptical. Therefore to improve the theory effectiveness of the theory, the media should increase the understanding of the issues by reporting a more detail information about the election with wide range of information.In addition, the media can also carry out a survey to understand better the level of absorption information of the readers, listeners a nd viewers. The media should also aware of the public acceptance and understanding of the issues as the agenda-setting theory has its own limitations in dispersing the news. Conclusion In conclusion, the Agenda Setting Theory is a very important practice in media industry especially in a democratic country like Malaysia. The media collaborate with government to control what to be think and discussed among the public.The purpose is to shape their perception over certain issues. It can be from a political issue to welfare issue. This theory proved that whatever issue has been discussed shape the importance of that specific issue and bring to the discussion in the public as in the public agenda. If the public or majorities think that there are some dissatisfactions or objections going on, there will be changes in the policy agenda. Thus, agenda setting is a very important tool in media even though there are still some weaknesses in this practice.So, the media should take in to account to improve their practice by injecting more information not only to a specific area but make it more widely than today in order for the public to have more knowledge about our nation and this may create a more critical thinking nation. References Agenda-Setting Theory – Maxwell McCombs and Donald Shaw(n. d. ). Retrieved July 30, 2010, from http://www. ninosoriadeveyra. com/uploads/3/0/1/1/3011660/agenda-setting_ justine_kate_gian. ppt. Agenda-Setting Theory: Presentation paper & abstracts (n. . ). Retrieved July 30, 2010, from http://realhomepages. com/wecapps/agenda%20setting. htm Agenda-Setting Theory: Strengths and weaknesses of theory (n. d. ). Retrieved July 30, 2010, from http://www. servinghistory. com/topics/Agenda-setting_theory::sub::Strengths_And_ Weaknesses_Of_Theory Garson, G. D. (2006). Agenda setting theory. Retrieved July 30, 2010, from http://faculty. chass. ncsu. edu/garson/PA765/agendasetting. htm Media Tenor Innovatio – Agenda setting theory (n. d. ).Retrieved July 30, 2010, from http:// www. agendasetting. com/res_theory. php M. Sanchez Spring 2002. (2002). Retrieved July 30, 2010, from http://zimmer. csufresno. edu/~ johnca/spch100/7-4-agenda. htm Spring 2001 theory workbook. (2001). Retrieved July 30, 2010, from http://www. uky. edu/~ drlane/capstone/mass/agenda. htm The Agenda-Setting Role of the Mass Media in the Shaping of Public Opinion (n. d. ). Retrieved July 30, 2010 from http://www. infoamerica. org/documentos_pdf/mccombs01. pdf